Biogenic Amines

Biogenic Amines

Biogenic amines formation in food is objectionable due to their ability to have a direct or indirect effect on the human vascular and nervous systems. Toxicological effects such as hypertension, headache, diarrhea, rash and localized inflammation may be developed due to biogenic amines and when ingested in extreme amounts, cardiac palpitation, intracerebral haemorrhage and even death in very severe cases (Rawles et al., 1996). Biogenic amines are considered precursors of carcinogenic amines such as N–nitrasosamines, and they also used as indicators of food decomposition (Mietz and Karmas, 1978). Histamine represents the major and the main cause of scombroid (histamine) poisoning, and the other biogenic amine such as tyramine, cadaverine, and putrescine, acts as potentiates of histamine toxicity (Taylor, 1988; AlBulushi et al., 2009; Joshi and Bhoir, 2011). ... Show more content on Helpwriting.net ...In humans the highest histamine concentrations are found in the skin, lung and stomach, with smaller amounts in the brain and heart, histamine is made and stored within white blood cells. When the immune system is activated in response to foreign material entering the body, histamine is the first defense chemical or correctly inflammatory mediator, released in the process called inflammation i.e. the clinical evidence that the immune system is responding (Joneja and Carmona,

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