Polycystic Ovarian Syndrome Analysis

Polycystic Ovarian Syndrome Analysis

The ovary is a critical organ of the female reproductive and endocrine system. When preforming in an optimal manner, the ovary functions as a gonad, by producing mature gametes and by synthesizing and excreting hormones within a set point. It is essential for sexual maturation and reproduction. When it deviates away from this normal physiology, many serious heath problems can emerge. A principal example of ovarian abnormal physiology is polycystic ovarian syndrome (PCOS). Polycystic ovarian syndrome is one of the most prominent endocrinopathies in the world, affecting anywhere between 5–10% of the female population (Dunaif, 1995). Although this disease affects so many women, not much is known about the exact origin of it and all of the shortcomings ... Show more content on Helpwriting.net ...Normally, each ovary is formed by dense tissue encircled by fibrous connective tissue. Starting at age of puberty, the ovaries become fixed with around 300,000 follicles, with each one containing an immature ovum. Through cyclic changes, 1 or 2 of these follicles become mature, releasing an oocyte, and thus resulting in fertilization or menstruation (Stanfield, 2012, p.646). However, with polycystic ovarian syndrome these cyclic changes are effected. Polycystic ovarian syndrome is defined by many symptoms, however, numerous cysts on the ovaries and chronic anovulation from hormone imbalances, normally characterize it. Chronic anovulation is described as infrequent or nonexistent ovulation. This symptom is directly correlated with infertility and is one of the largest identifying factors of polycystic ovarian syndrome. It is a result of nonclassical congenital adrenal hyperplasia (NC–CAH), an autosomal disease. This disorder is caused by a CYP21 (21–hyroxylase) gene mutation and thus, is lacked in the body. Due to its absence, 17–OHP (17–hydroxyprogesterone) amounts climb and the anterior pituitary gland secrets excess amounts of adrenocorticotropic hormone (ACTH) (Leung, 2004). The adrenocorticotropic hormone controls the amount of steroid hormones, which in return

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