Polycystic Ovary Syndrome Case Study
"Adolescent female with polycystic ovary syndrome manifested as depression"
To the Editor: Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder affecting 5–10% of women in the reproductive age group (5,13). PCOS is diagnosed according to Rotterdam criteria, when at least two out of three criteria are met: presence of polycystic ovaries, anovulation and/or oligoovulation and excess androgen activity not associated with another endocrine pathology (11,12).
Risk Factors/Pathogenesis: The pathogenesis of polycystic ovary syndrome is not known, and potential etiologies are explored in a recent review (8). PCOS is currently identified as a "complex multi–genetic disorder". It has a strong genetic component as evidenced by familial ... Show more content on Helpwriting.net ...Mother and patient denies any current environmental stressors, but does report that for last 1.5 years, minor was having growth of unwanted hairs on chin and weight gain, which has resulted in isolation and avoiding social settings. Minor was in a usual state of mental health about 2 years ago with satisfactory academic performance and social lifestyle. Minor was described by her parents as an average student, but currently her performance has been declining gradually and working below her potential. Her depressive symptoms consisted of anhedonia, lack of motivation, guilt, tearfulness, shame, embarrassment, hypersomnia, and difficulties in concentration. Denies any symptoms of mania, psychosis or emotional trauma or any other psychosocial stressors. Minor denies any substance abuse or use of medications such as Valproic acid. Denies any deaths or losses in immediate family. Family history is significant for diabetes mellitus in mother. On mental status examination she appeared obese. She seemed dysphoric. She answers questions slowly and thoughtfully and does not speak spontaneously. Her affect was constricted and sad. She described her mood as "depressed for as long as I can remember." She reports feeling tired with heaviness in her arms and legs. Patient endorses suicidal thoughts with a plan to overdose. She denied auditory and visual hallucinations. Her judgement and insight was poor, as she mentioned that she wanted to die to get out of her miserable mood. The psychiatrist send the minor to her pediatrician for work–up for hirsutism. The workup done showed cysts in the ovary and elevated testosterone, LH, LH/FSH ratio, DHEAS. The pediatrician in collaboration with the endocrinologist diagnosed minor with Polycystic ovary syndrome
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