Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome

Polycystic ovarian syndrome (PCOS) is the most prevalent endocrine abnormality of reproductive–aged women, occurring between 10 and 21% (March et al., 2010). Due to its complexity, PCOS is associated with a spectrum of symptoms, including amenorrhea, anovulation, hirsutism, acne, and obesity. All of which are subjective and do not allow for a definitive diagnosis. Long term complications, such as infertility, insulin resistance, dyslipidemia, depression, and anxiety require an early diagnosis; but establishing a comprehensive diagnostic criterion has been difficult (Teede et al., 2011). Historically, Stein and Leventhal first identified PCOS in 1935 when they associated it with hirsutism, chronic anovulation, obesity, and bilateral ovarian ... Show more content on Helpwriting.net ...Clinical signs of PCOS should also be confirmed through biochemical assays for all patients, and instead of only meeting two out of the three criteria, adolescents should meet four out of the five following criteria: oligo–amenorrhea at least 2 years after menarche, clinical and biochemical hyperandrogenism, insulin resistance or hyperinsulinemia, and polycystic ovaries on ultrasound with biochemical evidence (Sultan & Paris, 2006). There have even been numerous task forces calling for a revision of the Rotterdam criteria, particularly with regards to the definition of hyperandrogenism (Azziz et al., 2009). However, practitioners have endorsed none of these revisions. The purpose of this study was to establish the importance of biochemical assays in achieving early diagnosis of PCOS. Our results may provide a basis for an amendment of the Rotterdam criterion to improve diagnosis of PCOS in all patients, but especially

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